New and emerging immune-targeted drugs for the treatment of multiple sclerosis
نویسندگان
چکیده
منابع مشابه
Immune Rebound: Multiple Sclerosis after Treatment of Cushing’s disease
High cortisol level in endogenous Cushing’s syndrome suppresses the immune system and after treatment there may be an over activity of immune reaction leading to autoimmune diseases mostly thyroid and rheumatologic disorders. This is the second reported case of multiple sclerosis developing after treatment of Cushing’s syndrome. A 42-year old man is reported who presented with bone fracture and...
متن کاملEmerging therapies for treatment of multiple sclerosis
In the last decade, a new armamentarium of immune-based therapies have been developed and tested in patients with multiple sclerosis. Some of these therapies are showing a high level of efficacy, with an acceptable adverse effect profile. Because present therapies have significant limitations in slowing disease progression, require injections, are sometimes associated with significant side effe...
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This review discusses the mechanisms of action of 4 immune modulating drugs currently used in the treatment of multiple sclerosis (MS), including Alemtuzumab, a humanized monoclonal antibody that functions by targeting CD52, an antigen primarily expressed on T and B lymphocytes and monocytes/macrophages, resulting in their depletion and subsequent repopulation; Dimethyl fumarate that switches c...
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چکیده ندارد.
15 صفحه اولReview of New Methods of Diagnosis and Treatment of Multiple Sclerosis
Multiple sclerosis (MS) is a demyelinating process involving mainly the white matter of central nervous system. The clinical diagnosis generally rests on two features of the illness: A. A history of fluctuations in the clinical course. B. A physical examination consistent with that of multiple lesionsjinllheiwhite matter o,f the central nervous system. No specific laboratory test is cur...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2014
ISSN: 0306-5251
DOI: 10.1111/bcp.12285